福井県下の百日咳に関する疫学的検討(1986〜1991)--特に培養陽性患者について
スポンサーリンク
概要
- 論文の詳細を見る
In order to clarify the epidemiological situation of whooping cough in Fukui prefecture, 478 nasopharyngeal swabs from patients with pertussis-like symptoms were submitted to bacterial isolation. Laboratory data of these patients with clinical informations at the departments of pediatrics of 6 hospitals in Fukui city from June 1986 to May 1991 were also examined in relation to the above bacterial isolation. The results observed in culture positive patients were as follows:<BR>1) B. pertussis were isolated from 83 patients (41 men and 42 women). 2) Isolates were classified into 3 serotypes. Most dominant type was 1 · 3 · 6 (80 strains, 96.4%), and followed by 1 (2 strains) and 1 · 4 · 5 (1 strain). 3) Most of the patients were non-vaccinees less than 3 years of age (69 of 83 (83.1%). This evidence suggested strongly that pertussis vaccine was highly effective to prevent pertussis. 4) The patients under 3 years of age whose leucocyte counts were ≥15000/mm<SUP>3</SUP> and lymphocyte rate to total leucocyte were ≥70% in their peripheral blood at the time of nasopharyngeal swabs sampling were only 49.3%(33 of 67). Therefore, diagnosis of pertussis by leucocyte findings alone were considered to be inadequate. 5) The area of the patient's residence covered 7 regions of 8 health center districts in Fukui prefecture. The areal distribution of the number of patients from June 1986 to May 1991 was relatively proportional to the population of each district. 6) The number of patients in these 5 years showed apparently yearly variations and the similar variations were observed in a rate of positive antibody to <I>B. pertussis</I> toxin (PT) and filamentous hemagglutinin (FHA) in the children from 1986 to 1990. It seemed to be important to examine the above yearly variations for pertussis epidemiology in the future. 7) Isolation rates of <I>B. pertussis</I> from nasopharyngeal swabs of patients were significantly higher on HG-SS media newly designed by us in comparison with those on Bordet-Gengeu medium and Cyclodextrin Solid Medium (CSM).
- 日本感染症学会の論文
日本感染症学会 | 論文
- 看護学生における風疹, 麻疹, 水痘, ムンプス感染防止対策 : 抗体価測定とワクチン接種
- 本邦において初めて流行が確認された小児の human metapneumovirus 感染症の臨床的, 疫学的解析
- つつが虫病および日本紅斑熱について発生頻度が異なる地域での市民医学講座参加者における認知度比較
- 日本の検疫所における遠隔疫学調査による多剤耐性赤痢菌株のインド国内における定着の証明
- HIV-1感染者血清中の逆転写酵素活性阻止抗体の動態