栃木県の1979年7月から1980年6月までのブタ血清に対するA型インフルエンザウイルスの血清疫学的研究
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概要
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Seroepizootiological studies were carried out on swine in Tochigi Prefecture over a period from July, 1979 to June, 1980. In them, estimation was made on titers of HI antibody against type A influenza virus in the serum of these swine, and transitional antibody examined in swine spontaneously infected with this virus. Then the following results were obtained.<BR>1) The porcine type A strain caused an epizootic repeatedly among swine. When such epizootic broke out, it spread remarkably and HI antibody of high titer was acquired. The rate of possession of HI antibody sometimes reached 100% among swine raised in an area involved in such epizootic.<BR>2) The Hongkong type A strain did not cause such an intense epizootic as that of the porcine type A strain. The rate of possession of antibody against the A/Bangkok/1/79 strain, as estimated each month, ranged from 10 to 50% among pork-type swine. It was generally observed that this strain induced a persistent mild epizootic.<BR>3) Swine positive for antibody against the A/Bangkok/1/79 strain were used to study the rise and fall of some other Hongkong type A strains. As a result, the rate of antibody possession was 19.2% not only against recently prevailing strains but also against such old strains as the A/Yamanashi/20/75/strain.<BR>4) It was found that 2 swine were positive for antibody against the Russion type A strain.<BR>5) The transmission of antibody against type A influenza virus from the mother sow to the colostrum, regular milk, and piglet serum depended upon the level of antibody titer of the mother sow. It was demonstrated that when the mother sow showed an HI antibody titer of 1: 2, 048 against the A/NJ/8/76 strain, her colostrum exhibited a titer of 1: 1, 024, her regular milk a titer of 1: 256, and the serum of her piglet one month old a titer of 1: 64, presenting the transmission of antibody from her. The antibody titer become below 1: 16 in her piglets at 2 or 3 months of age.
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