猩紅熱流行のあった1学級における咽頭溶連菌の調査 (猩紅熱研究年次報告論文,研究資料集 1975年〜1976年)
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概要
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In November 1975, we observed 5 cases of scarlet fever from a classroom of the first grade in an elementary school in Sapporo. In this classroom and other one as control, throat cultures for 13-hemolytic streptococci were carried out. This examination was attempted 3 times for the period from December 1975 to February 1976.<BR>The results were as follows:<BR>1. In this classroom the isolation rate of P-hemolytic streptococci was 64.1%, on the other hand in another classroom which had no scarlet fever patient was 19.1%.<BR>2. The higher level of isolation rate in this classroom was observed during 3 months with 3 times examinations.<BR>3. Oral administration of antibiotics (ABPC) which was parformed to only the children who carried f3-hemolytic streptococci was effective to decrease the number of the carriers.<BR>4. Serotyping of the strains isolated from the children in this classroom revealed T28, T6, T4, T3, and T12, among them T28 and T6 were the predominant types, especially T28 was observed in 56.0%. In this connection, however, we couldn't obtain T28 but found T6 from 3 cases out of 5 cases of scarlet fever. Fom 2 remainder patients any p-hemolytic streptococci was not revealed.<BR>5. 5 strains isolated from 3 patients showed the same pattern on drugs susceptibility tests against 7 kinds of antibiotics, but we couldn't find out this pattern among 65 strains isolated from the children in concerned 2 classrooms.<BR>6. As for isolation rate we found out little difference between the streak plate method and the pour plate method, and could elevate the isolation rate by employing these 2 methods at the same time.
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