尿路感染症に対するTalampicillinの検討 (タランピシリン論文集)
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概要
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In two cases with normal renal function, the blood levels reached the maximum (4.3μg/ml, 4.5μg/ml) at 1-2 hours after administration of Talampicillin 500 mg per os. In three cases with impaired renal function, the blood levels reached the maximum (7.6μg/ml-9.0μg/ml) at 2-4 hours after administration of Talampicillin 500 mg per os at fasting time.<BR>The urinary recovery were 146.8 mg and 144.8 mg during 6 hours after administration of Talampicillin 500 mg per os in two cases with normal renal function.<BR>Sixty-two cases with lower urinary tract infections were treated with Talampicillin 750 mg per day per os. Excellent or good results were obtained in 42 cases. Side effects were observed in 9 cases of this series 4 were gastro-intestinal symptoms and 5 were skin eruption. Talampicillin administration was discontinued in 2 cases of them.
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