Estimation of Residual Volume Fraction of the Ventricle with Incomplete Mixing by an Indicator Dilution Method

概要

論文の詳細を見る
The conventional dilution method of estimating residual volume fraction (RVF) of the ventricle is based on the assumption of complete intraventricular mixing of the indicator. However, incomplete mixing in the ventricle has been observed in various ways. A dilution method is devised for estimating RVF in spite of incomplete intraventricular mixing of the indicator; RVF=Cγ, i/Cγ, i-1/Cγ, i/Cγ, i-1+ (1-Cγ, i/Cγ, i-1) Cγ, i/Cs, i where Cγ, i/Cγ, i-1=the ratio of the concentration of the indicator in the residual volume in the i th cardiac cycle Cγ, i to that in the (i-1) th cycle Cγ, i-1, and Cγ, i/Cs, i=the ratio of Cγ, i to the concentration of the indicator in the stroke volume in the i th cardiac cycle Cs, i. This method is used in the canine heart for assessment of the incompleteness of mixing and for comparison of RVF by the conventional and the new method. Results show that some incompleteness of mixing is generally observed, but RVF by the conventional method is considered approximately equal to that by the new method. Some model analysis of incomplete mixing is given for explanation of the experimental data.
一般社団法人日本生体医工学会の論文