Evaluation of Cardiac Contractility of Human Left Ventricular Myocardial Wall Using MRI with Tagging Technique.

概要

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Two-dimensional deformation of human left ventricles (Subjects were eight normal volunteers and a patient with hypertrophic cardiomyopathy) during the ejection period was investigated using MRI with the tagging technique. The regional displacements and strains in the myocardial wall were analyzed from the motions of intersections of tagged stripes formed in the short-axis images. The results for normal volunteers showed that the magnitudes of displacement differed among various regions (anterior, septal, posterior and lateral) of the left ventricle, but the magnitudes and the directions of the minimum principal strain were almost uniform over all regions. The magnitude of the minimum principal strain in the anterior wall of the patient with hypertrophic cardiomyopathy clearly decreased compared with that of normal volunteers. The study strongly suggested that the minimum principle strain could be a new effective index to evaluate cardiac contractility.
一般社団法人日本生体医工学会の論文