タイトル無し
スポンサーリンク
概要
- 論文の詳細を見る
In this study, a neural network model is proposed to obtain -the numerical description of pain mechanisms. The model simulates peripheral receptors, afferent L- and S-fibers and the receptive cells of the spinal cord area Adaptation effect and conduction velocity of each fiber are considered in the model. The activities of peripheral and spinal cord neural cells are represented by the Wilson-Cowan's differential equation, considering the ongoing activity of neurons. Pain and touch sensibilities are estimated by the firing activities of lamina V (Transmission, T) cells and lamina IV cells, respectively.<BR>The results of model simulation have been obtained for single square-wave pulse and periodic pulse sequences applied on peripheral receptors. The duration of initial bursts of T and IV cells, which occur soon after the beginning of stimulation, depends on the stimulus intensity and approaches a plateau with increasing intensity. In case the stimulus intensity is increased above the threshold of S-fibers, secondary burst of T cells appears about 50 msec after the stimulation, which is equivalent to the conduction time of S-fibers from the periphery towards the spinal cord cells. High-frequency and high-intensity stimulation gives the typical firing patterns of pain modality, represented by the high secondary burst of T cells which continues during the stimulation. From the results of periodic pulse stimulation, the so-called pain and absolute threshold characteristics have been obtained and have been compared with the results of cutaneous electrical stimulation. Both results are shown by quite a similar relationship between stimulus pulse frequency and stimulus intensity and their characteristics are given by the power function's law of frequency and intensity.<BR>The proposed neural network model mimics the pain modality very well, and the results of simulation are in good agreement with some of physiological and experimental results.
- 一般社団法人 日本生体医工学会の論文
一般社団法人 日本生体医工学会 | 論文
- Evaluating the Workload Reduction of Automatic Vital Data Transmission
- Mental Fatigue Measurement Based on the Changes in Flicker Perception Threshold using Consumer Mobile Devices
- A Theoretical Study on a Computational Algorithm for Human Posture Estimation Based on Motion Capture of a Small Number of Markers
- Latest microscopic technique. From the principle to application. Development of three-dimensional microscopic system for operation of mini-pig fertilized eggs.
- A Study of the Automation of Cytodiagnosis (The Second Report):Cytophotometry Using Photomicroscanner and a Trial of Data-processing