:Application of Receiver Operating Characteristics (ROC) Curve and Information Capacity
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概要
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Quantitative and objective evaluation for the rate of correct diagnosis in the doctor's reading of X-ray images is very difficult to make, but is very important especially in the case of mass screening. We studied two X-ray diagnostic systems used in mass screening, that is, (1) congenital dislocation of hip-joints in newborn infants and (2) cancer of the stomach. Both diseases are more frequently found in this country compared to other nationalities. As the methods of evaluation, receiver operating characteristics (ROC) curve and information capacity were employed. For the former disease, radiographs of 200 hip-joints were read by five specialists and six orthopedists. Out of 200 joints, 26 were confirmed to be abnormal and 174, normal. Percentages of true positive (TP) and false positive (FP) were obtained from the results of interpretation of the doctors mentioned above. On the other hand, two diagnostic methods using simple anatomical geometry were evaluated for their diagnostic abilities by tracing manually the edge of bones and measuring the geometrical features. The methods used were (1) Hilgenreiner's height (<I>H</I>) and (2) Uziie's angle (β). The ROC plots of the two methods were compared with those of the doctors. It was found that Uziie's angle had a better diagnostic ability than Hilgenreiner's height and, moreover, it proved to be almost identical with that of the average specialists.<BR>For the latter disease, results of radiographic interpretation for confirmed cases of stomach cancer were mainly obtained from the data file of the Center for Adult Diseases, Osaka City. In this case, the ROC curve was drawn using percentage TP and FP obtained as a function of confidence level of malignancy, and several X-ray imaging systems for stomach were intercompared. The evaluation of this study is still preliminary, but it will serve as a basis for further investigation on optimization for screening in stomach cancer.
- 一般社団法人 日本生体医工学会の論文
一般社団法人 日本生体医工学会 | 論文
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