Summary Facial paralysis induced by intra-arterial infusion and radiotherapy ; report of two cases

概要

論文の詳細を見る
Many complications accompanied with intra-arterial infusion and radiotherapy for head and neck cancer have been reported. Among them facial paralysis is ralatively rare. Researchers say, the incidence of it has been about 5-9 % and its prognosis is usually benign. Two cases of it with preceding damage of auricle are reported. Case 1: 84-year-old woman with maxillar carcinoma. Treatment was intra-arterial infusion of 5-Fluorouracil (5-FU) through the superficial temporal artery and radiotherapy. Total dose of them were 6, 000 mg and 50 Gy. Erosion of the auricle occured at first and then perichondritis, and soon facial paralysis followed. The paralysis was recovered completely after eight weeks, but auricle was necrotizing and f alled into decay. Case 2 : 71-year-old man with maxillar carcinoma. Method of therapy in this case was same as case 1, but the total dose of 5-FU and radiation differed from that, 6, 250 mg and 47.5 Gy was given. Inflammation of auricle appeared and facial paralysis occurred soon after the end of series of infusion and radiation. His auricle came to be well cured, but facial paralysis has not improved yet. It is concluded that facial paralysis and inflammation of auricle in such cases is considered to be caused by ischemic change of the external carotid artery area.
特定非営利活動法人日本頭頸部外科学会の論文