Relationship between Immunity and Interferon Production in Macrophages:III. Enhancement of Interferon Production by Antiserum

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概要

• 論文の詳細を見る

• The effect of antiserum on the interferon (IF) production in macrophages by Newcastle disease virus (NDV) has been studied. Completely neutralized NDV lost its IF-inducing ability, but under-neutralized NDV revealed an enhanced IF-inducing capability. This enhancement of IF production by unneutralized NDV was also observed in antiserum-treated cells. Enhancement phenomena appeared to be based on immunological specificity. Under- neutralized NDV was also adsorbed more rapidly and at a higher rate to normal cells than unneutralized NDV. Unneutralized NDV also adsorbed more efficiently to antiserum-treated cells and to cells derived from immunized mice than to normal cells. The significance of these phenomena is discussed in relation to the induction mechanism of IF in macrophages

• 財団法人 学会誌刊行センターの論文

著者

• AZUMA Masanobu

  Department of Bacteriology, Hokkaido University School of Medicine

• YAMADA Morihide

  Department of Bacteriology, Hokkaido University School of Medicine

• NISHIOKA Rikichi

  Department of Bacteriology, Hokkaido University School of Medicine

関連論文

• Relationship between Immunity and Interferon Production in Macrophages:III. Enhancement of Interferon Production by Antiserum
• Relationship between Immunity and Interferon Production in Macrophages:II. Molecular Weights of Interferon Produced in Macrophage Cultures

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