Estimation of Reference Ranges in Shizuoka Prefecture by the Revised Hoffmann's Fitting Method-Comparison with Reference Ranges in Fukuoka Prefecture and Those Obtained by a Nonlinear Optimization Method-:—Comparison with Reference Ranges in Fukuoka Prefe
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We calculated sex-age dependent reference intervals for 15 items on the basis of health examination data of 156, 565 persons in Shizuoka prefecture. Data were obtained from three laboratories, and intervals were calculated by the revised Hoffman's method. We compared these reference intervals with two reference ranges with reference ranges widely accepted in studies of the Japanese population: the Fukuoka medical association reference ranges as well as the sex-and age-dependent reference ranges of Ohgushi et al., which were obtained by a nonlinear optimization method at Tokai University.<BR>In particular, specific comparisons were made between the data we obtained and the sex-and age-specific data obtained by Ohgushi et al. from about 750, 000 persons assessed at 14 laboratories. Slight disparity was observed in some factors, but sex-and age-dependent trends in glucose, uric acid, total cholesterol concentration and alkaline phosphatase activities coincided closely between the two data sets. The factors showing disparity require further examination; the calculation procedure should be considered as well as any particular characteristic of reference groups in Shizuoka prefecture.<BR>Our finding indicated that if compatibility between laboratories could be guaranteed by means of an external quality control investigation, reference intervals should be determined in large-scale co-operative studies and that collaborative use of these reference intervals by multiple laboratories would be possible.
- 一般社団法人 日本総合健診医学会の論文
一般社団法人 日本総合健診医学会 | 論文
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