Modification of the Bioluminescent Bacterial Genotoxicity Test and Application to Genotoxicity Monitoring of Waste Landfill Leachate.
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概要
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The Mutatox<SUP>TM</SUP> test (commercial name for the bioluminescent bacterial genotoxicity test) method for investigating genotoxicity using dark mutants of marine luminous bacteria was modified as a simple method for application to genotoxicity monitoring of waste landfill leachate. The modified test was rapid, operationally simple genotoxicity test that was able to experiment many samples by using the 96-well plate compared with the Mutatox<SUP>TM</SUP> test having to experiment with the special cuvettes. All 10 samples of waste landfill leachate were shown to genotoxic potency by this test with or without S9. It was suggested that the modified bioluminescent bacterial genotoxicity test was better simply and sensitivity than the Ames test or the SCE test in mammalian cell culture experimented, and was suitable method of genotoxicity monitoring of waste landfill leachate.
- 日本環境化学会の論文
日本環境化学会 | 論文
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