The Clinical Use of 203Hg-Salyrgan in Renal Diseases

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We examined fundamental and clinical studies of kidney by 203Hg-Salyrgan and the results were obtained as follows. We know that the chief distributed organ of 203Hg-Salyrgan is the kidney and on the autoradio gram the blackend dots there are predominantly into the distal tubuli. Disappearance of 203Hg-Salyrgan from blood stream in the normal adults gets to half within 16 min and in the patients with renal diseases the disappearance to half takes longer. The rate of prolongation were almost parallel with severity of illness. It seemed reasonable that the simultaneous combination of nephrography and scintiphotography by 203Hg-Salyrgan would also supply the information of the renal function that could not be obtained from the usual procedure alone. We think that the method of 203Hg-Salyrgan is a kind of the most useful research technique for evidence of the damage in renal parenchyma with the low exposure dose in kidney tissues.
社団法人日本アイソトープ協会の論文