Bloom's Syndrome Presenting with Malignant Lymphoma of the Duodenum; Case Report.
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概要
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A 7-year-old boy suffering from Bloom's syndrome (BS) developed a submucosal tumor in the duodenum. Following a subtotal resection, the diagnosis was made as non-Hodgkin's lymphoma (diffuse mixed type and B-cell type). The patient was in stage IV with bone marrow involvement. The patient was treated according to the B-8801 protocol of TCCSG (Tokyo Children's Cancer Study Group). A reduction of anticancer agents to half of the scheduled doses was required due to hematological toxicity and severe mucositis. He has been disease-free for a year after the completion of a 12-month chemotherapy protocol. Our case requires careful follow-up study including late adverse effects and for a second malignancy. Previous reports from Japan revealed that 8 of 16 patients with BS developed malignant neoplasms.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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