Results of treatment in pediatric non-Hodgkin's lymphoma.
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概要
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Twenty-six children with non-Hodgkin's lymphoma were treated between 1977 and 1988. Fifteen of them were treated with CHOP, COMP, and LSA5L2 protocol before 1984, eleven were treated with CCLSG protocols (NHL-8201, NHL-855) after 1985 until 1988. Induction rate was 85%; overall failure-free survival rate was 45%. There were no relapses after 17 months since treatment started. Eighteen of the 26 patients were in advanced stages : stages III, IV : ten who were treated before 1984 relapsed in 17 months; failure-free survival rate of eight who were treated after 1985 until 1988 was 45%. Of eight relapsed children, 5 were lymphoblastic type; these 5 died of the diseases. Two of the rest were small non-cleaved types; the other was diffuse large cell type. Two lymphomas, one small non-cleaved type, and one diffuse large cell type have survived twelve and sixty-one months. In conclusion, there are some difficulties in improving the prognosis of pediatric lymphomas, especially lymphoblastic lymphomas.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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