Two Cases of Opportunistic Mycoses Treated with Micafungin in the Patients Receiving Allogeneic Stem Cell Transplantation
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In this paper, we describe two acute lymphoid leukemia cases with invasive fungal infection in allogeneic stem cell transplanation. One suffered from fungal hepatosplenic abscess without identification of causal species and the other had pulmonary aspergillosis as a result of neutropenia following intensive chemotherapy and allogeneic stem cell transplantation. Their diseases were refractory to amphotericin B and nephrotoxicity developed. Therefore, amphotericin B was replaced with micafungin in both cases. In both patients, clinical and laboratory findings got better and hepatosplenic abscess and pulmonary aspergillosis were almost healed without adverse reaction. Thus, micafungin appears to be a useful and safe anti-fungal agent for refractory invasive fungal infection including aspergillus infection in children undergoing stem cell transplantation.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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