Peripheral Blood Stem Cell Transplantation for an Infantile Case of Mixed Lineage Leukemia.
スポンサーリンク
概要
- 論文の詳細を見る
n one-year-3-month-old boy was admitted to our hospital because of anemia, thrombocytopenia and subcutaneous bleeding. He was subsequently diagnosed as having acute mixed lineage leukemia (MLL) by surface marker analysis. The chromosome abnormality of leukemic cells was 47, XY, +21, 12p+. The complete remission was achieved by intensive chemotherapy. We performed the peripheral blood stem cell autotransplantation (PBSCT) when he was 2 years and 11 months old. Seven months after the PBSCT, chromosomal analysis of his bone marrow cells showed 47, XY, +21, 12p+. This abnormality, which was the same one revealed at the time of first admission to our hospital, was found only in one cell out of 20 examined cells. Then we began to treat him with the adjuvant therapy of 6-mercaptopurine and prednisolone for about 7 months. We think that PBSCT is safe and effective therapy for MLL in childhood ; however, adjuvant therapy is necessary for cases showing minimal residual disease after receiving PBSCT.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
- The Parent's Emotional Adaptation to the Children's Malignant Disease
- Side Effect of Cranial Radiation in Childhood Acute Leukemia
- Red Blood Cell Volume Distribution Width in Normal Children and in the Patients with Various Kinds of Hematological Disorders.
- Effective Conditioning of Donors for Granulocyte Transfusions with Recombinant Human Granulocyte Colony-Stimulating Factor.
- Two Infant Girls of CNS Leukemia with Chronic Subdural Hematoma