The Effect of Ventricular Pacing Rates on the Left Ventricular Volumes
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概要
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The relations of the left ventricular volumes of the intact canine hearts, such as stroke volume (<I>SV</I>), end-diastolic volume (<I>EDV</I>) and end-systolic volume (<I>ESV</I>), to the heart rates were studied. After the atrio-ventricular node was blocked by injecting a small amount of formalin, ventricular pacing was induced. Varying the pacing rates, the left ventricular volumes were measured by means of thermal dilution using a thermistor with a very short time constant. The results showed that under left atrial pressure clamp, increases in pacing rates ranging from 50 to 160 beats/min caused decreases in <I>EDV</I> to considerable extents but no consistent and large changes in <I>ESV</I>. Measurements of the left ventricular end-diastolic pressure (<I>LVEDP</I>) under left atrial pressure clamp demonstrated that reductions in <I>EDV</I> at higher pacing rates were caused by lowering of <I>LVEDP</I>. From these results, some mathematical expressions on the control of <I>SV</I> are presented.
- 一般社団法人 日本生体医工学会の論文
一般社団法人 日本生体医工学会 | 論文
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