Therapeutic effects of new anti-inflammatory drug, 2-(4-(2-thiazolyloxy)phenyl)propionic acid (156-S), on postoperative pain after removal of impacted teeth. A double blind controlled study for comparison with indomethacin.:A double blind controlled study
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The therapeutic effects of 2- [4- (2-thiazolyloxy) phenyl] propionic acid (156-S) were compared with those of indomethacin (IND) in patients with pain after surgical removal of impacted teeth.<BR>One hundred sixty patients were randomly divided into 2 groups : group I received 300 mg of 156-S and group II received 25 mg of IND, all orally and at the onset of pain.<BR>The clinical effects of each drug were statistically analysed in 130 (63 of group I and 67 of group II) of 160 patients, and the following results were obtained:<BR>1) The analgesic effect appeared in a significantly shorter time in group I than in group II.<BR>2) The analgesic effect one hour after the administration of the drugs was significantly greater in group I than in group II.<BR>3) The analgesic effect lasted considerably longer in group II than in group I.<BR>4) No specific adverse reactions were detected with the drugs.
- 日本歯科薬物療法学会の論文
日本歯科薬物療法学会 | 論文
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