Clinical effect of Midecamycin acetate on the oral infections.

概要

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The results of clinical studies on MOM for oral use, performed at 22 institutes in this country, are summarized in this protocol. The conclusions obtained is as follows: 1) Clinical efficacy of MOM oral administration was evaluated in 113 patients with oral infectious disease, and 82.3% responded to the drug. 2) Clinical efficacy of MOM at a daily dose of 600 mg was 83.2% based on committee-judgement and 80.0% based on doctors' judgement. 3) MOM shows antibacterial activity against aerobes, anaerobes and mixed infection cases. 4) In 4 of the 160 cases treated, gastrointestinal symptoms were appeared. 5) From the above results, it was concluded that MOM was a useful new antibiotic for the treatment of oral infections.
日本歯科薬物療法学会の論文