Clinical effects of Tsumura Hangeshashintoh for the desease of oral mucosa.

概要

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Oriental traditional medicine"Tsumura Hangeshashintoh"which contains Pinelliae Tuber, Scutellariae Radix, Glycyrrhizae Radix, Zizyphi Fructus, Ginseng Radix, Coptidis Rhizoma, Zingiberis Siccatum Rhizoma, was used for 28 patients aged from 10 to 67 years old who had suffered oral mucosa lesion from January to August in 1984. The daily dose was 7.5 g taken orally and admitted 2.5 g before every meal. The results were as follows : 1) The evaluation of the clinical effects were taken after 2 and 4 weeks. The clinical improvement after 4 weeks held glossitis 70.0%, lichen planus 71.4%, recurrent aphtha 100%, aphthous stomatitis 100%, and hairy tongue 25.0%, and the total effectiveness was 71.4%. So that this drug was pretty effective without hairy tongue. 2) The clinical usefulness obtained were glossitis 60.0%, lichen planus 71.4%, recurrent aphtha 100%, aphthous stomatitis 66.7%, and hairy tongue 25.0%, and the total usefulness was 64.3%. 3) Of relation between the disease and symptoms, 82.1% of the patients held neurotic or abdominal symptoms. And they agreed with the oriental medical"shoh" for"Hangeshashintoh." 4) No abnormalities or side effects were observed during clinical examination. We found"Tsumura Hangeshashintoh"was effective for the disease of oral mucosa at first choice.
日本歯科薬物療法学会の論文