Clinical study of analgesic, anti-inflammatory, and anti-pyretic agent, Ketoprofen (Capisten) injectable in management of pain and fever in oral surgery.

概要

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We administered Ketoprofen injectable to 22 cases (19 patients) with pain and 4 cases (4 patients) with fever, treated at the Department of Dentistry and Oral Maxillofacial Surgery, Medical College of Oita, between June 1983 to March 1984. We examined its analgesic and anti-pyretic effect, and obtained the following results. 1) To 22 cases with pain and 4 cases with fever, Ketoprofen injectable 50mg was added up to twice a day in cases with fever and three times in cases with pain. 2) In all cases, the results of improvement were devided into four classes. Then the ratio of remarkable improvement was 34.6% (9/26), the moderate improvement was 50.0% (13/26) and the ratio of both was 84.6%. 3) The ratio of its remarkable usefulness was 26.9% (7/26), the usefulness 53.8% (14/26) and the ratio of both 80.8%. 4) The side effects were observed in two out of 26 cases (7.7%), but these two cases were recorded from one patient with different periods. Therefore, the side effects were observed only in one out of 23 patients (4.3%) . From above mentioned results we could conclude that the Ketoprofen injectable was an effective and useful non-steroidal analgesic, anti-inflammatory and anti-pyretic agent with big safety in the field of oral and maxillofacial surgery.
日本歯科薬物療法学会の論文