Clinicostatistical analyses of methicillin-resistant Staphylococcus aureus (MRSA) detected in inpatients

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In the present study, clinicostatistical analyses were made of 11 MRSA-infected or detected cases in our department (Jan. '91 to Dec. 2001) . The analytical results were as follows: 1) The 11 inpatients, ranging from 30 to 90 years of age, consisted of oral cancers (8), malignant lymphoma (1), mandibular fracture (1) and buccal abscess (1) . The male to female ratio was 10: 1. 2) Age, physiological conditions, hospitalization period and antibiotics used were considered as infection factors. Eight inpatients were more than 65 years old. Three patients suffered from diabetes mellitus and 7 patients were in relatively long-term hospitalization. 3) The antibiotics used were mainly of the cephem (56.5%) and penicillin (13.1%) types. Of the 11 cases, 8 (72.7%) showed MRSA-infected or -detected onset within 29 days after the start of antibiotics. 4) The co-existing bacteria detected were gram-positive ones, such as Staphylococcus epidermidis, α-streptococcus and Peptostreptococcus. 5) MRSA-infected or -detected cases were classified into two groups based on clinicopathologic state as follows: 5 complete MRSA-infection cases and 6 only MRSA-detected cases without common symptoms. The former group reacted well to only vancomycine and the latter group was clinically cured also by cephems.
日本歯科薬物療法学会の論文