A study on the effects of local anesthetics for dental pulp and lip. Using ORA Inj. Cartridge compared with Xylocaine Inj. Cartridge for Dental Use.:—Using ORA<SUP>®</SUP> Inj. Cartridge compared with Xylocaine<SUP>®</SUP>Inj. Cartridge for Dental Use—
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The solution of 2% lidocaine hydrochloride containing a vasoconstrictor, epinephrine in the concentration of 1/80, 000 is frequently used as a local anesthetic in odontotherapy.<BR>We had chance to use 2% lidocaine hydrochloride solution with epinephrine bitartrate (ORA Inj. Cartridge), which had approximately the same epinephrine concentration as the preparation above. Thus the effects of infiltration anesthesia on dental pulps and lips were studied in volunteers. For comparison, Xylocaine inj. (cartridge form) was widely used.<BR>Subject teeth were upper front teeth of each volunteer (students and staffs of Nihon University, School of Dentistry) .<BR>For local anesthesia, each anesthetic was injected into the supraperiosteal in apical area. The injection volume and time were 0.5m1 and 30 sec.<BR>Prior to anesthesia, the threshold to electrical stimulation on pulpal sensation for each volunteer was measured by an electrical pulp testing apparatus (Pyocure) . On that pulp, the time before anesthesia took effect and duration of the action after injection of a local anesthetic depended on the observed loss and recovery time of pulpal sensation by electrical stimulation corresponding with the threshold value. The effect of anesthesia after injection of anesthetic on the lip was judged by the response of each volunteer.<BR>The anesthetic effects of ORA inj. on pulps and lips were manifested in about 78 and 109 sec. and lasted about 184 and 161 min., respectively. The effects of Xylocaine inj, on pulps and lips were manifested in about 111 and 74 sec. and lasted about 145 and 140 min, respectively.
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