Clinical evaluation of Cefodizime(CDZM, Kenicef) in various infections in the field of oral surgery.

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Clinical evaluation of cefodizime (CDZM, Kenicef®) in various infections in the field of oral surgery were carried out. Cefodizime was administered by intravenous injection at a daily dose of 2g (1g× 2times) to 102 patients with various infections. Cases consisted of 86 with maxillary ostitis, 4 pericoronitis, 3 odontogenic maxillary sinusitis, 3 phlegmon of the oral floor, 2 alveolar ostitis, 2 phlegmon of the buccal region, 1 peritonsillar abscess, and 1 angina. The following results were obtained : The clinical effects obtained in subjective judgement were classified as excellent in 60 cases, good in 35 cases, fair in 5 and poor in 2. The clinical effects obtained in judgement by point were classified as excellent in 31 cases. eood in 66 and poor in 5. Effective rate in subject was 93.1 %. Effective rate in judgement by point was 95.1 %. There were no cases with side effects. In the laboratory examinations, thrombocytosis in 2 cases, elevations of s-GOT and s-GPT in one case were observed. The result indicated the usefulness of cefodizime in the treatment of various infections in the field of oral surgery.
日本歯科薬物療法学会の論文