Effects of Cefotaxime on Coagulation System.

概要

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Cefotaxime was administered to 21 cases in oral regions and studied on laboratory parameters concerning peripheral blood: blood plateret counts, prothorombin time (PT), hapaplastin test (HPT), active partial thromboplastin time (APTT) and protein induced by vitamin K absence (PIVKA II) . The results obtained were summarized as follows, <BR>Clinical bleeding symptoms were not observed in any of these cases.<BR>1. blood plateret counts: Abnormal values were not observed.<BR>2. Coaguration system (PT, HPT, APTT, PIVKA II) : Significant changes were not found in these values.<BR>We have concluded that incidences of abnormal hemostatic test following CTX administration are rare. It was suggestted that CTX is one of the reliable antibiotics in oral regions.
日本歯科薬物療法学会の論文