Clinical evaluation of topical applicant, TSG-88 for periodontal disease.

概要

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An evaluation of TSG-88, which contains soluble azulene (sodium azulene sulfonate), cetyl pyridinium chloride and alminium chlorohydroxyallantoinate and is prepared for patient home use to improve periodontal disease, was performed in a clinical application for 64 patients with symptoms of gingivitis and periodontitis, who consisted of 31 maled and 33 females aged 15 to 65 years. All patients offered the therapy of TSG-88 were checked clinicaly an improvement on symptoms and participated the quetionarie. 14 cases were scored by means of Gingival Index and Bleeding Index. The results obtained were as follows. 1) The improvement on symptoms was obviously observed in 80.8% of gingivitis patients and 74.2% of periodontitis patients. 2) Bleeding and pus exudation were significantly improved and their efficiency was show on Gingival Index and Bleeding Index. 3) No side effect was observed among all cases employed. 4) 96.0% of all patients didn't feel discomfort when TSG-88 was applied into oral cavity. Consequently, it was suggested that the application of TSG-88 on gingival tissue by patient is effective as a part of periodontal treatment.
日本歯科薬物療法学会の論文