The analgesic effect of ampiroxicam on postoperative pain after removal of lower impacted wisdom tooth.

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The analgesic effect of ampiroxicam on postoperative pain after removal of the lower impacted wisdom tooth was clinically evaluated by a double blind test with indomethacin. After a 27 mg dose of ampiroxicam was confirmed to be sufficient to relieve the postoperative pain in a preliminary study, the clinical effect of a 27mg dose of ampiroxicam given in 153 cases (APM group) was compared to that of a 25mg dose of indomethacin in 152 cases (IND group) . The results were as follows : 1) 22 of the 29 cases in the preliminary test and 227 of the total 305 cases in the double blind test needed analgesics after extraction of the lower impacted wisdom tooth. 2) The preliminary study showed that 27mg of ampiroxicam was clinically sufficient to relieve postoperative pain after extraction of the lower impacted wisdom tooth. 3) The double blind test revealed that the pain was markedly relieved in 10.9% of the APM group and 12.0% of the IND group and over moderately in 69.1% of the APM group and 55.6% of the IND group. The analgesic effect was higher in the APM group than in the IND group although both analgesics controlled pain well. 4) Side effects were observed in only two cases. One was skin eruption in the preliminary APM's study and the other was slight vomiting in the IND group. 5) The usefulness of analgesics as assessed by oral and maxillofacial surgeons was higher in the APM group than in the IND group. The "markedly useful" rating was 11.8% in the APM group and 12.0% in the IND group, and the over "useful" rating was 70.0% in the APM group and 56.5% in the IND group. 6) These results indicate that the administration of 27mg of ampiroxicam will be useful in relieving postoperative pain after extraction of the impacted lower wisdom tooth.
日本歯科薬物療法学会の論文

The analgesic effect of ampiroxicam on postoperative pain after removal of lower impacted wisdom tooth.

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日本歯科薬物療法学会 | 論文

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