Acinic cell carcinoma derived from the mucous membrane of lower lip. A case report.

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An extremely rare case of acinic cell carcinoma derived from the mucous membrane of lower lip is reported. A 72-year-old woman consulted a physician for a big pedunculated mass (60×40×40mm) in the left lower lip, with bleeding and respiratory disturbance. The patient was referred to our clinic for detailed examination and treatment by a physician.<BR>Radiological examination and initial biopsy were performed. The diagnosis was suspected malignant tumor and its metastasis. Tumorectomy and total neck dissection were performed for malignant tumor. Estlander's flap was used for repairment in defect of the lip. On the basis of histological findings of surgical specimens including primary tumor and lymph nodes of submental and submandibular regions, acinic cell carcinoma and its metastasis were confirmed. Intercalated duct-like cells were identified in the electron micrographs of the tumor cells, and intercalated duct-like cells were regarded as the histogenesis of tumor cells. The patient demonstrated no recurrence and functional disturbance for 51 months after operation.
一般社団法人日本口腔腫瘍学会の論文