Estimation of therapeutic method and prognosis of carcinoma of the buccal mucosa.

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During a fifteen year period from May 1976 to December 1990, we treated nineteen primary patients with squamous cell carcinoma of buccal mucosa at the Department of Oral Surgery, Tokyo Metropolitan Komagome Hospital. The average age of the patients was 70.6 years. This study analyses the treatment and results.<BR>(1) TNM staging of the series after the UICC recommendation revealed that the majority of the patients were in advanced stages T3 and T4. Of these cases, 62.3% were NO, and all cases were M0.<BR>(2) We chose two types of therapeutic modality for the initial treatment: the surgery group and irradiation group. Nine cases (50%) were treated by radiotherapy alone, two cases by a combination of irradiation therapy and surgery, and three cases by surgery alone. The primary tumor control rate for each type of therapy was 44.4%, 0 %, and 100%, respectively. By staging, stage III was 37.5% and stage IV was 100%. By location, buccal mucosa was 57.1% and retromolar area was 50.0%.<BR>(3) The five-year cumulative survival rates were 55.1% in the 19 cases of buccal mucosa carcinoma (T1: 66.7%, T2: 64.8%, T3: 34.3%, T4: 53.3%) . The surgery group showed a higher survival rate (76.5%, surgery alone was 100%) than the irradiation group (36.8%, radiotherapy alone was 40.9%) .
一般社団法人日本口腔腫瘍学会の論文