A case of verruciform xanthoma in the palatal mucosa.

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A case of verruciform xanthoma in the palatal mucosa was reported. The patient was a 46-year-old man with a 1-year history of a rough surface of the palatal mucosa. Oral examination revealed a well circumscribed and broad based lesion of whitishyellow color, with a granular surface and 15×12 mm in size, in the palatal mucosa of the right upper molar region. No other significant findings were noticed. The lesion was diagnosed as a verruciform xanthoma (papillary type) by histopathologic examination of biopsy material, and was surgically excised. Histopathologically, the lesion was composed of both hyperparakeratotic stratified squamous epithelium with regularly elongated rete pegs and numerous foamy cells in the connective tissue of inter-rete ridges. Foamy cells were surrounded by dense connective tissue with partial hyalinization. No recurrence occurred for 2 years and 6 months after surgical treatment.
一般社団法人日本口腔腫瘍学会の論文