A clinicopathological study on 40 cases of squamous cell carcinoma of the upper alveolus and gingiva.

概要

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Forty patients having squamous cell carcinoma of the upper alveolus and gingiva were analyzed clinicopathologically. These patients were treated radically at Second Department of Oral and Maxillof acial Surgery, Osaka Dental University, from 1980 to 1996. TNM classification of these cases was T1: 6, T2: 17, T3: 8, T4: 9, N0: 27, N1: 12, N2: 1, and M0 cases: 40. The results were as follows 1. Local control rate for T1, T2, T3 and T4 were 100%, 88%, 86% and 50%, and for anterior site, molar site and posterior site of primary involvement were 100%, 87% and 57% respectively. 2. Histologic metastasis to cervical lymph nodes were f ouod in 15 cases (37.5%), and secondary cervical metastasis in 5 cases of T3 and/or T4. 3. The cause of death was primary failure in 5 cases, neck lymph node failure in 5 cases and distant metastasis in 1 case. 4. Cases of T3, T4 and/or posterior site lesions showed poor prognosis. 5. High score group of histological malignancy grade showed poor prognosis conpared to low and moderate score group. 6. The cumulative 5-year survival rates for T1, T2, T3, T4 and all cases were 100%, 84%, 47%, 47% and 69% respectively.
一般社団法人日本口腔腫瘍学会の論文