Initial calcification processes inside the pores of porous hydroxyapatite ceramics implanted in the submandibular glands of rats.:Initial calcification processes inside the pores of porous hydroxyapatite ceramics implanted in the submandibular glands of r

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The initial calcification processes inside the po res of porous hydroxyapatite ceramics implanted into the submandibular salivary glands of rats were observed by light -microscopy and by scanning and transmission electron-microscopy at varying int ervals for 10 weeks after implantation.The inorgani c elements inside the pores were examined by line- and surface-analysis with x-ray-d etection energy-dispersive analysis.<BR>The porous hydroxyapatite ceramics were encapsulated with a layer of fibrous tissue during the later stages, although during the earlier stages the surr ounding tissues showed inflammatory phenomena.Insid e the pores of the implants, two types of calcification processes were observed. The first type was devoid of cells or any collagen fibrils, whereas in the second type, fibroblast-like cells, whichi nvaded the pores of the implants, and collagen fibrils appeared to be associated with the initial calcification processes.
歯科基礎医学会の論文