Biological properties of oral trichomonads. Phagocytosis, production of short-chain fatty acids and EB virus induction.:phagocytosis, production of short-chain fatty acids and EB virus induction

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In the present study, the phagocytosis of latex particles and Staphyloco ccus aureus by Trichomonas tenax was examined, and production of short-chain fatty acids and induction of EB virus antigen were also investigated. Larger latex particles (1.07μm in size) were enclosed sparsely by T. tenax and smaller size particles (0.15μm) were found to have accumulated within T. tenax cells. T. tenax began to enclose S. aureus into its cytoplasm after 10 minutes, and the action of phagocytosis of S. aureus by T. tenaxdeclined within 24 hours. Electron microscopic findings indicated that phagocytosis had initiated within 10 minutes, followed by the degradation of bacterial cells within 24 hours. Acetic acid of 2.6 mM as a short-chain fatty acid in 5 ml of cultured fluids was producedby T. tenax and 2.0 mM by T. vavinalis, respectively. In addition, 1.0 mM acetic acid was produced by the isolated accompanying bacteria. These cultured fluids did not induce the EB viral antigens in terms of early antigen (EA). The result obtained in the present study disclosed that S. aureus was enclosed and digested in the cytoplasm within 2 hours, besides, the cultured fluids of these trichomonad species did not induce EA because the inducers such as n-butyric acid could not be yielded.
歯科基礎医学会の論文