Positional distribution of fatty acids in phosphatidylcholine and phosphatidylethanolamine from rat sublingual salivary gland.
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概要
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The <I>sn</I>-1 position of phosphatidylcholine from rat sublingual gland was highly occupied by saturated fatty acids, palmitate and stearate. Arachidonate and linoleate were exclusively located at the <I>sn</I>-2 position. Such asymmetry was also observed in phosphatidylethanolamine, although considerable amounts of alkenyl moieties were present at the <I>sn</I>-1 position. Based on their contents, it was suggested that the most abundant molecular species of phosphatidylcholine and phosphatidylethanolamine are 1-palmitoyl-2-arachidonoyl and 1-stearoyl-or 1-alkenyl-2-arachidonoyl (plasmalogen) types, respectively. Chronic administration of isoproterenol which causes an increase of linoleoyl-phospholipids in parotid and submandibular glands did not affect the positional distribution of fatty acids in phosphatidylcholine and phosphatidylethanolamine from the sublingual gland.
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