:V-V. Cell damage due to extract of Actinomyces viscosus and A. naeslundii

概要

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The purpose of this investigation has been to demonstrate the presence of direct tissue damage agents in extract of Actinomyces viscosus and A. naeslundii to cultured cell. L-cells were cultured in MEM media to which extract of the bacteria with various concentrations were added, and proliferating rate, colony formation degree and cell persistence level were observed.<BR>Suppression of L-cell's proliferation was observed in the groups which were added ×40 and ×20 diluted extract. Decrease of colony formation degree and cell persistence level were also noted in these groups. In a group which was added ×10 diluted extract, non-proliferation, non-colony formation and non-persistence were seen.<BR>From the above results, it was indicated that extract of Actinomyces had a possibility of damaging periodontal tissue directly by their components.
歯科基礎医学会の論文