:Localization in gingival tissue and PCA activity of fusobacterial antibody
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概要
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The relationship between Fusobacterium and periodontal disease has been investigatedby many reseacher. The present study was made to clarify the possibility of periodontal tissueinjuries which might be developed by immediate type hypersensitivity produced by Fusobacterium.The results obtained were as follows:<BR>1) Fluorescent conjuated protein antigen which was obtained from a water soluble fractionof Fusobacterium by ammonium sulfate precipitation and polyacrylamide gel electrophoresis showedspecific fluorescence on the surface of the lymphoid cells (especially plasma cells) infiltrated inseven of fifteen cases of inflamed human gingiva.<BR>2) Rabbit antisera to Fusobacterium was capable of causing passive cutaneous anaphylaxisin guinea pigs.<BR>Our investigations demonstrated that Fusobacterium in the gingival sulcus stimulate theproduction of anti-Fusobacterial antibody and the antibody may cause injuries to the periodontal tissue through immediate type hypersensitivity.
- 歯科基礎医学会の論文
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