Thermoradiotherapy for Colorectal Carcinoma.
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概要
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The Japanese Society for Therapeutic Radiology and Oncology conducted a survey ofthe present state of thermoradiotherapy for colorectal carcinomas in Japan. In this survey, 105cases at the 9 institutions were registered which had been treated from January 1981 to December 1992. From this data, we analyzed the trend of hyperthermia for the colorectal carcinoma and the treatment parameters which might have an influence on the treatment results.<BR>1) Ninety-four of 105 cases were recurrent or metastatic lesions.<BR>2) Mainly, the RF capacitive heating equipment were applied for the colorectal carcinoma.<BR>3) The number of cases in which hyperthermia were given once or twice a week were almostequal, and there, was no significant difference in the treatment response rate.<BR>4) The mean duration of hyperthermia at therapeutic temperature was 42 min. Measurements oftemperature in lesions were performed in 86% of sessions, and the mean tumor temperaturewas 43.1°C<BR>5) Higher maximum tumor temperature and longer treatment time have brought significantly better response.<BR>6) Responder groups have shown better survival than non-responder groups.<BR>7) Acute reactions associated with hyperthermia were as follows: pain in 35 cases, burn and/orskin erosion in 12 cases, abscess formation in 3 cases and others in 3 cases. Late effects oftreatment were ileus in 9 cases, ulcer of intestinal tract in 5 cases, subcutaneous' fibrosis in 3and others in 6.<BR>In conclusion, the application of thermoradiotherapy for reflactory colorectal carcinoma maycontribute to the improvement of prognosis and quality of life of patients.
- 一般社団法人 日本放射線腫瘍学会の論文
一般社団法人 日本放射線腫瘍学会 | 論文
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- Thermoradiotherapy for Colorectal Carcinoma.
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