Treatment of Pediatric Acute Rhinosinusitis with and without Allergic Rhinitis

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we studied the effect of atopy or allergic rhinitis on the results of treatment of pediatric acute rhinosinusitis in a prospective study. Forty children with acute rhinosinusitis (27 boys and 13 girls, age 4-10 yeas, mean age 6.1±2.5 years) were recruited. The subjects were first treated with an antibiotic, i. e., clarithromycin, penicillin, or cephem, for less than one week, and low-dose clarithromycin was continued for three weeks, without any other drugs, including anti-allergic drugs. Response to treatment was judged on the basis of changes in symptoms, nasal findings by ENT specialists, and radiographs of the maxillary sinus. The results showed no effect of atopy or allergic rhinitis on the results of treatment of pediatric acute rhinosinusitis. However, some subjects with allergic rhinitis showed improvement in objective findings, but not in their symptoms. Such patients may develop a negative impression of treatment of acute rhinosinusitis.
日本鼻科学会の論文