A case of gingival hyperplasia induced by nifedipine.

概要

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Gingival hyperplasia induced by Biphenyl hydantoin has been well docummented.<BR>Recently reports have become available on gingival hyperplasia induced by the vasodilating drug Nifedipine, which is clinically and histologically similar to Piphenyl Hydantoin induced gingival hyperplasia.<BR>We encountered a case of Nifedipine-induced gingival hyperplasia and performed gingivectomy after oral hygiene measures, this resulted in uneventful recovery, with no signs of recurrence.<BR>The Nifedipine-induced gingival hyperplasia is rare and the mechanisms of action of Nifedipine are not clarified at present. But it is expected that the number of cases of Nifedipine-induced gingival hyperplasia may increase in Japan.<BR>Thus we should consider the mode of chemotherapy and attempt to improve periodontal gingival treatment.
日本歯科薬物療法学会の論文