Blood and saliva levels of TE-031.

概要

論文の詳細を見る
TE-031 is a peroral macrolides antimicrobial agent. This drug belongs to a group of new macrolides which are synthesized from Erythromycin. <I>In vitro</I>, the susceptibility of microorganisms to this drug is the same as Erythromycin, however, it exhibits superior distribution to tissues as well as superior for urinary excretion.<BR>In this study, the blood and saliva concentrations of TE-031 were compared by a crossover test in 10 healthy volunteers who were perorally given 150 mg of this drug while fasting and after a meal.<BR>The distributions of the blood and saliva concentrations show similar patterns for fasting and after a meal. It is suggested that TE-031 is little influenced by food.
日本歯科薬物療法学会の論文