A clinical study of the analgesic effect of the non-steroid anti-inflammatory agent, amfenac sodium (Fenazox) on pain after exodontias and minor operations.
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The non-steroidal anti-inflammatory agent, Amfenac sodium (Fenazox<SUP>®</SUP>, 1 capsule 50 mg) was administered to 118 cases at pain time after exodontias and minor operations at our clinic between December, 1986 and May, 1987.<BR>Out of 118 cases, 61 were able to be evaluated. We classified the 61 cases into 4 groups, i.e. Group 1; usual exodontias, Group 2 ; surgical exodontias (underwent bone cutting), Group 3 ; operations on soft tissue, Group 4 ; operation on hard tissue.<BR>The analgesic effects were evaluated with estimation by the patients using selt-checking cards and by the doctors. The following results were obtained :<BR>1) In 43 cases (70%), analgesic effects appeared within 30 min after receiving 1 capsule of Amfenac sodium, and in 58 cases (95%) within 1 h.<BR>2) Transition of the degree of pain for each group are displayed in Figs. 2-5. These figures show that the analgesic effect appeared about 30 min after administration and lasted for 3-4h.<BR>3) Total effects were classified into 4 grades, "excellent" in 38 cases (62%), "effective" in 12 cases (20%), "slightly effective" in 10 cases (16%), and "non-effective" in 1 case (2%) .<BR>4) Side effects were recorded in 4 cases (7%), but they were mild and disappeared soon without any treatment.<BR>5) Total usefulness was classified into 5 grades, "highly useful" in 36 cases (59%), "useful" in 13 cases (21%), "slightly useful" in 11 cases (18%), "not useful" in 1 case (2%), and "worse" in no cases.<BR>According to the results, the non-steroidal anti-inflammatory agent, Amfenac sodium (Fenazox<SUP>®</SUP>) was effective for pain after exodontias and minor operations and was also safe and useful. It is worth noting that the analgesic effect appeared rapidly.
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