Trends in the use of analgesic anti-inflammatory drugs and anti-inflammatory enzymatic drugs in dental practice survey among 17 private dental colleges and university hospitals in Japan.
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Among the drug therapy, given in dentistry, the use of analgesic anti-inflammatory drugs occupies a large share along with antibiotics.<BR>According to a survey made by Yohkoh et al. in 1983, the consumption of analgesic anti-inflammatory drugs accounted for 27.8% of the total consumption of internal medicines, outstripping that of antibiotics which made up 23.4%.<BR>We have investigated the kinds and shares of consumption of analgesic, analgesic anti-inflammatory drugs and anti-inflammatory enzymatic drugs according to the prescriptions issued by 17 private dental college hospitals throughout Japan between October 15th to 21st, 1984.<BR>Of all the prescriptions, those including analgesic and analgesic anti-inflammatory drugs amounted to 48.9%. The prescriptions as written by item (each prescription) totalled 31.7% of all.<BR>The prescriptions which included anti-inflammatory enzymatic drugs made up 9.1 %, where 84% of these anti-inflammatory enzymatic drugs were prescribed for concurrent use with antibiotics.<BR>The drug most frequently used as an analgesic was Sedes G, followed by Aspirin preparations.<BR>The drugs most frequently used among analgesic anti-inflammatory drugs were 2 kinds of 250 mg mefenamic acid capsules and diclofenac sodium tablets, making up as much as 38% of the total consumption during this study.<BR>The drug most frequently used among anti-inflammatory enzyme preparations was seratio peptidase. The second most popular drug was the 30 mg tablet of lysozyme chloride preparation.<BR>Though the development of analgesic anti-inflammatory preparations has decreased recently, the trends now show that characteristic drugs are introduced to the maket in succession.<BR>Careful consideration, therefore, is essential to the selection of these preparation.
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