Clinical study on intraoral minor salivary gland tumor. Part 2: Treatment and clinical course.:Part 2: Treatment and clinical course

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• The treatment and clinical course of 157 intraoral minor salivary gland tumors at the Department of Oral and Maxillofacial Surgery, Hokkaido University School of Dentistry from August 1967 to July 1992 were reviewed and clinically analyzed.<BR>The results were as follows:<BR>1. Of the 94 benign tumors, 70 cases were treated with excision, 23 cases with extirpation, and 1 case with cryosurgery.<BR>2. Of the benign tumors, 3 cases of 50 pleomorphic adenoma recurred.<BR>3. Of the 63 malignant tumors, 41 cases were treated with surgery (S) alone, 11 cases with surgery and irradiation (R), 1 case with surgery, irradiation (R), and chemotherapy (C), 7 case with irradiation alone, and 3 cases with (R+C) .<BR>4. Overall 5, 10, 15, and 20-year cumulative survival rates of malignant tumors were 76.9 %, 63.6%, 44.0%, 32.1%, respectively.<BR>5. Of 59 primary malignant tumors, the 10-year cumulative survival rate in each clinical stage was 90.0% (stage I), 69.2%, (stage II), 50.0% (stage III), 42.6% (stage IV), 62.3% (all stage) ; at each primary site was 83.9% (floor of the mouth), 71.4% (mucosa of the cheeks), 60.1% (palate), 50.0% (retromolar areas), 25.0% (alveolus) ; in each histopathological classification was 70.3% (adenoid cystic carcinoma), 68.2% (mucoepidermoid carcinoma), 66.7% (carcinoma in pleomorpic adenoma), 20.0% (adno-carcinoma) ; and for each treatment was 76.1% (surgery alone), 72.7% (S+R, S+R+C), 10.0 % (R, R+C) .<BR>6. Of 59 primary malignant tumors, during the clinical course, cervical lymphonodus metastasis and distant metastasis were found in 15 cases and 18 cases (15 lung), respectively. After primary treatment, recurrence and residual of tumor were found in 11 cases and 3 cases, respectively. The incidence of distant metastasis, recurrence, and residual of tumor were high in adenoid cystic carcinoma.

• 一般社団法人 日本口腔腫瘍学会の論文

一般社団法人 日本口腔腫瘍学会 | 論文

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