Therapeutic results for squamous cell carcinoma of upper gingiva and alveolus.
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概要
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Control rates of primary lesion and cervical lymph node metastasis and 5-year-cumulative survival rate were evaluated for 43 primary cases of carcinoma of upper gingiva and alveolus. There were 4 cases of stage I, 13 of stage II, 9 of stage III, and 17 of stage IV, and the primary lesions of 3 cases were seen in the anterior subdivisional region, 29 in the lateral subdivisonal region, and 11 in the posterior subdivisional region. Eleven, 5, and 27 cases received surgery, radiation, and combination therapy with surgery, radiation, and/or chemotherapy, respectively, as the initial therapy. The control rates of the primary lesions in cases that received surgery and radiation were 65.8% and 20.0%, respectively. The control rates of the primary lesions were low in the T4 cases of the lateral subdivisional region and posterior subdivisional region. It is suggested that extraoral surgical approach and the combination of the radiation therapy are needed to improve the control rate of the primary lesions. The cervical lesions were controlled at 6 out of 8 sites (4 of 6 cases), which could be evaluated in this study. Of these cases, 2 of 4 cases died of metastasis at the opposite site, and the other 2 cases died of distant metastasis. Bilateral lymph node metastasis was seen in 5 of 6 cases. These results suggest that contralateral or bilateral elective neck dissection may be recommended for patients with positive neck node or T4 cases of lateral subdivisional region. The cumulative 5-year-survival rates in cases that received surgery and the total cases were 50.2 % and 42.9 %, respectively.
- 一般社団法人 日本口腔腫瘍学会の論文
一般社団法人 日本口腔腫瘍学会 | 論文
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