Intraosseous carcinoma arising in periapical lesion of the mandible: Report of a case.
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概要
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A case of intraosseous squamous cell carcinoma of the mandible, presumed to have arisen from the odontogenic epithelium in periapical lesion, is reported. A 48-year-old Japanese female was ref eyed to our clinic complaining of an abnormal sensation in the left side of her lower lip. A firm mass under the mucogingival fold in premolar-molar region of the left mandible was palpable, but no abnormality was found in the overlying oral mucosa. Radiographic examination revealed poorly demarcated round radiolucency around the apex of the second premolar. Two orthopanoramic X-rays taken by her family dentist 40 months and 22 months ago showed well-demarcated small periapical radiolucency in the tooth. The pathological diagnosis of the biopsy specimen was squamous cell carcinoma. Segmental resection of the mandible and total neck dissection was performed becauce no other distant primary focus was detected by systemic survey. There was no evidence of metastasis or local recurrence 15 months after the operation. Histopathology of the surgical specimen revealed that the squamous cell carcinoma extended from the periapical region of the second premolar to the buccal soft tissue breaking through the mandibular cortical plate. But the overlying oral mucosa was intact and made no contact with the subjacent carcinoma itself. Histopathological evidence of pre-existing radicular cysts was not confirmed, and no metastasis was detected in dissected lymph nodes.
- 一般社団法人 日本口腔腫瘍学会の論文
一般社団法人 日本口腔腫瘍学会 | 論文
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