Analysis of patients with Stage I tongue cancer who underwent excisional biopsy.
スポンサーリンク
概要
- 論文の詳細を見る
Twenty-six patients with stage I tongue cancer, who underwent excisional biopsy in our clinic between April, 1980 and December 1995, were retrospectively analyzed, focusing on the relationship between pathological findings and secondary neck metastasis (SNM) . Results obtained were as follows.<BR>1. SNM developed in 26.9 % of 26 the cases and was found within 5-15 months after surgery. Two cases metastasized to level I, 2 cases to level II, and 3 cases to levels I & II. The number of metastasized lymph nodes was 1-5.<BR>2. As the pathological tumor size (pT) became larger, tumor cells invaded deeper, revealing that pT in cases that invaded into the muscular layer was 13.1±2.8 mm, which was statistically significant at p<0.01 in comparison with other cases.<BR>3. SNM developed in 20 % of 5 cases that invaded on the border of the muscular layer, and in 40 % of 15 cases that invaded into the muscular layer. However, there was no correlation between pT and SNM.<BR>4. In regard to grading by WHO, SNM was found in 27.8 % of patients in Grade I, in 16.7 % of those in Grade II, and in 50.0 % of those in Grade III.<BR>5. As to mode of invasion by Yamamoto, et al., no SNM developed in patients who belonged to mode 1 and 2. In mode 3 patients, however, 20.0 % developed SNM, as did 71.4 % of patients in mode 4C.<BR>6. There was no correlation between lymphatic invasion in the resected specimens and SNM.<BR>7. Because 7 cases that developed SNM revealed extranodular invasion pathologically, all but two cases underwent irradiation (22-54Gy), and three of them furthermore underwent chemotherapy.<BR>8. The 5-year cumulative survival rate in this series was 71.1 %.<BR>9. We feel that elective neck dissection should be done in cases that measure more than 10 mm in pT, that invade into the muscular layer, and belong to mode 4C (and/or 4D), even though they may be stage I tongue cancers.
- 一般社団法人 日本口腔腫瘍学会の論文
一般社団法人 日本口腔腫瘍学会 | 論文
- 進行口腔癌に対する逆行性超選択的動注化学療法, 放射線同時併用療法後の救済手術
- TS-1による化学療法と温熱放射線療法が著効した後発頸部リンパ節転移の1例
- 手術シミュレーションに基づく腫瘍分割摘出により顎骨を保存した得た下顎骨骨形成線維腫の1例
- 口腔癌における化学・放射線療法後の再発・二次再建に関する外科療法の検討
- 下顎骨再建 : 血管柄付遊離骨移植と遊離軟部組織移植の比較