:II. Application of human permanent teeth

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It was previously reported by us that fluoride treatment followed by a lanthanum solution treatment (F-La treatment) to synthetic apatite powder provided higher resistance to acid solution than acidulated phosphate-fluoride treatment (APF treatment). In this paper, the two step treatment has been successfully extended to apatite sinter and human permanent teeth to investigate the possibility of application for dental caries prevention.<BR>The surface of the apatite sinter with the F-La treatment was covered with spherical compounds which consisted of calcium fluoride and amorphous lanthanum fluoride based on SEM analysis. These compounds remained after the acid solubility test for 1 hr. Etching the human permanent teeth with phosphoric acid solution above one mol/<I>l</I> removed sufficient oral organic substances (pellicle), giving a chemically reactive surface. The human permanent teeth subjected with the F-La treatment had about two times higher acidic resistance than with the APF treatment. In the analysis by EPMA, lanthanum and fluorine were present about 15μm in depth from the enamel surface and remained after the acid solubility test for 1 hr.
歯科基礎医学会の論文