Immunopathological study of periodontal disease. VII Bacterial enzyme and periodontal disease (1) Bacterial chondroitinase ABC and hyaluronidase in dental plaque.:VII Bacterial enzyme and periodontal disease (1) Bacterial chondroitinase ABC and hyaluronid

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Existence of bacterial enzymes (chondroitinase ABC and hyaluronidase) in the dental plaque obtained from 50 volunteers (22 years old) and clinical health demonstrated by fluorescence antibody technique.<BR>Chondroitinase ABC was detected in the plaque of all volunteers and hyaluronidase was demonstrated in 44 of the 50 volunteers. Fluorescence of chondroitinase ABC and hyaluronidase was observed as a diffuse, granular or fibrillar pattern in the plaque. From these fluorescence patterns, it was indicated that the diffuse pattern represented the exudate from certain bacteria, and granular or fibrillar pattern showed localizationin in the cytoplasm of the bacteria. It was also suggested that the bacteria which produced chondroitinase ABC and hyaluronidase were a type of cocci or fusiforms.
歯科基礎医学会の論文