A Case of Chondrosarcoma in the Ethmoid Extending to the Skull Base

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We report a case of chondrosarcoma in the ethmoid extending to the anterior skull base. A 71-year-old woman complained of a right-sided nasal obstruction for one month prior to visiting a regional hospital. Under a tentative diagnosis of an ethmoidal tumor, an endonasal endoscopic biopsy was performed. The histopathological diagnosis was grade-II chondrosarcoma, and the patient was referred to our department. Computed tomography and magnetic resonance imaging revealed a tumor arising in the right ethmoid with extension to the orbit, nasal septum, sphenoid and cribriform plate. Ophthalmological findings were normal. She underwent tumor resection via a lateral rhinotomy combined with an anterior craniotomy followed by an immediate reconstruction of the skull base using a galeopericranial flap. Because the posterior surgical margin was microscopically tumor cell-positive, she was given postoperative radiotherapy (cyber knife). The patient is currently free from disease 6 months after surgery. The epidemiology, pathology, clinical characteristics and treatment of chondrosarcoma of the head and neck are reviewed.
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